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Production of Biologics and Chemical Drugs
from Natural Resources
BioGeneric Pharma developed unique technologies in purifying therapeutic
proteins and other compounds from natural resources, such as human urine, pig
intestine and plants. Using patented affinity resins, we have purified dozens
of proteins and chemical compounds with high purity and quality as final drugs
or APIs. Our products were exported to many other countries by collaborating
with our international partners. These products have been used to treat various
human diseases.
Genetic Engineering
Recombinant DNA technology has been common method to producing therapeutic
proteins and antibodies. Examples of such proteins using genetic engineering
include human interferon, EPO, TPA, GM-CSF. Humanized antibodies have been
drawing more and more attention because of their market potential and
technology in the field were breakthrough. BioGeneric Pharma established
molecular biology lab and will use own high expression vector system to
generate recombinant therapeutic proteins and antibodies in mammalian cells.
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Large Scale Production of Mammalian Cells
Mammalian cells have advantage of making proteins and antibodies with fully
post modification system such as glycosylation, phosphorylation. There is a
trend more and more genetically engineered drugs that have to be produced in
mammalian cells. Each gene product has its unique character and needs to be
optimized for certain cell line using customized media. We are setting up a
technology platforms including gene expression, selection of clones with high
level expression, cell adaptation and producing cell mass.
Production of Recombinant Proteins and Monoclonal Antibodies
Purification of proteins is BioGeneric Pharma specialty. By integrating
purification products from natural resources, we have established various
systems to accomplish our goals. We have integrated our patented affinity
purification systems with traditional methods including ion-exchange, gel
filtration, hydrophobic interaction chromatography and others.
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